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Chapter 17: Q. 20 (page 442)
What is a biomarker?
a. the color coding of different genes
b. a protein that is uniquely produced in a diseased
state
c. a molecule in the genome or proteome
d. a marker that is genetically inherited
Option b is correct.
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In 2011, the United States Preventative Services Task Force recommended against using the PSA test to screen healthy men for prostate cancer. Their recommendation is based on evidence that screening does not reduce the risk of death from prostate cancer. Prostate cancer often develops very slowly and does not cause problems, while the cancer treatment can have severe side effects. The PCA3 test is more accurate, but screening may still result in men who would not have been harmed by the cancer itself suffering side effects from treatment. What do you think? Should all healthy men be screened for prostate cancer using the PCA3 or PSA test? Should people in general be screened to find out if they have a genetic risk for cancer or other diseases?
Gene therapy can be used to introduce foreign DNA into cells ________.
a. for molecular cloning
b. by PCR
c. of tissues to cure inheritable disease
d. all of the above
Explain why metagenomics is probably the most revolutionary application of genomics.
The Flavr Savr Tomato:
a. is a variety of vine-ripened tomato in the supermarket
b. was created to have better flavour and shelf-life
c. does not undergo soft rot
d. all of the above
How has proteomics been used in cancer detection and treatment?
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