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Chapter 17: Q. 25 (page 442)

If you had a chance to get your genome sequenced, what are some questions you might be able to have answered about yourself?

Short Answer

Expert verified

Predicting Disease Risk at the Individual Level.

Step by step solution

01

Human Genome sequencing

Information about the entire human genome's six billion base pairs can be obtained by whole-genome sequencing.

02

Predicting disease risk 

Disease risk prediction includes screening currently healthy individuals using genome-wide analysis at the personal level. Healthcare providers may recommend lifestyle changes and medications before the onset of illness. This approach is most applicable when the problem is a defect in a single gene. Such defects account for only 5 percent of the disease in developed countries. The majority of prevalent diseases, including heart disease, are polygenic, or multifactorial, which is a phenotypic trait involving two or more genes as well as environmental factors like food.

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Most popular questions from this chapter

You are working in a molecular biology lab and, unbeknownst to you, your lab partner left the foreign genomic DNA that you are planning to clone on the lab bench overnight instead of storing it in the freezer. As a result, it was degraded by nucleases but still used in the experiment. The plasmid, on the other hand, is fine.

What results would you expect from your molecular cloning experiment?

a. There will be no colonies on the bacterial plate.

b. There will be blue colonies only.

c. There will be blue and white colonies.

d. They will be white colonies only

Information obtained by microscopic analysis of stained
chromosomes is used in:
a. radiation hybrid mapping
b. sequence mapping
c. RFLP mapping
d. cytogenetic mapping

In 2011, the United States Preventative Services Task Force recommended against using the PSA test to screen healthy men for prostate cancer. Their recommendation is based on evidence that screening does not reduce the risk of death from prostate cancer. Prostate cancer often develops very slowly and does not cause problems, while the cancer treatment can have severe side effects. The PCA3 test is more accurate, but screening may still result in men who would not have been harmed by the cancer itself suffering side effects from treatment. What do you think? Should all healthy men be screened for prostate cancer using the PCA3 or PSA test? Should people in general be screened to find out if they have a genetic risk for cancer or other diseases?

Genomics can be used in agriculture to:

a. generate new hybrid strains

b. improve disease resistance

c. improve yield

d. all of the above

What is a biomarker?

a. the color coding of different genes

b. a protein that is uniquely produced in a diseased
state

c. a molecule in the genome or proteome

d. a marker that is genetically inherited
See all solutions

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