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Chapter 16: Q. 17 (page 415)
An unprocessed pre-mRNA has the following structure.
Which of the following is not a possible size (in bp) of the mature mRNA? a. 205bp b. 180bp c. 150bp d. 100bp
Option a is correct.
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How can external stimuli alter post-transcriptional control of gene expression?
2. Targeted therapies are used in patients with a set gene expression pattern. A targeted therapy that prevents the activation of the estrogen receptor in breast cancer would be beneficial to which type of patient?
a. patients who express the EGFR receptor in normal cells
b. patients with a mutation that inactivates the estrogen receptor c. patients with lots of the estrogen receptor expressed in their tumor
d. patients that have no estrogen receptor expressed in their tumo
What could happen if a cell had too much of an
activating transcription factor present?
Alternative splicing has been estimated to occur in more than 95% of multi-exon genes. Which of the following is not an evolutionary advantage of alternative splicing? a. Alternative splicing increases diversity without increasing genome size. b. Different gene isoforms can be expressed in different tissues. c. Alternative splicing creates shorter mRNA transcripts. d. Different gene isoforms can be expressed during different stages of development.
A mutation within the promoter region can alter the transcription of a gene. Describe how this can happen
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