WHAT IF? There are three times as many Alu elements in the human genome as in the chimpanzee genome. How do you think these extra Alu elements arose in the human genome? Propose a role they might have played in the divergence of these two species.

Short Answer

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In the human genome, Alu elements must have undergone more active transposition than in chimpanzees. Differential duplications may have grown more prevalent when the number of recombination errors in the human genome grew due to an increase in Alu elements.

Step by step solution

01

Alu elements

Primate species possess Alu elements, which are transposable elements (TE) or jumping genes. TEs move across the genome, or hop from one place to another, occasionally inserting copies of themselves directly into protein-coding genes.

02

Genome

All genetic information about an organism is contained in its genome.Molecular sequences such as DNA and RNA are encoded in each cell of the body. The genome includes all the genes of an organism, including both coding and non-coding elements

03

Divergence

During the evolution of an organism, when two features develop out of a common ancestor that grew apart over time, the process is known as divergence. When a descendent species' population splits into two or more descendent species, its form and structure become progressively different.

The Alu elements are responsible for the divergence between the genomes of chimpanzees and humans, as they are more numerous in the human genome. Human impacts have also been linked to insertions or deletions of Alu in a number of situations.

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Most popular questions from this chapter

The ENCODE pilot project found that at least 75% of the genome is transcribed into RNAs, far more than could be accounted for by protein-coding genes. Review Concepts 17.3 and 18.3 and suggest some roles that these RNAs might play.

Below are the amino acid sequences (using the single-letter code; see Figure 5.14) of four short segments of the FOXP2 protein from six species: chimpanzee (C), orangutan (O), gorilla (G), rhesus macaque (R), mouse (M), and human (H). These segments contain all of the amino acid differences between the FOXP2 proteins of these species.

Use a highlighter to color any amino acid that varies among the species. (Color that amino acid in all sequences.)

  1. The C, G, R sequences are identical. Identify which lines correspond to those sequences.
  2. The H sequence differs from that of the C, G, R species at two amino acids. Underline the two differences in the H sequence.
  3. The O sequence differs from the C, G, R sequences at one amino acid (having V instead of A) and from the H sequence at three amino acids. Identify the O sequence.
  4. In the M sequence, circle the amino acid(s) that differ from the C, G, R sequences, and draw a square around those that differ from the H sequence.
  5. Primates and rodents diverged between 60 and 100 million years ago, and chimpanzees and humans about 6 million years ago. Compare the amino acid differences between the mouse and the C, G, R species with those between the human and the C, G, R species. What can you conclude?

The model of globin gene evolution shown in Figure 21.14 suggests that an ancestral gene is duplicated and mutated to become α- and β-globin genes, and then each one was further duplicated and mutated. What features of the data set to support the model?

Insects have three thoracic (trunk) segments. While researchers have found insect fossils with pairs of wings on all three segments, modern insects have wings or related structures on only the second and third segment. It turns out that in modern insects, Hox gene products act to inhibit wing formation on the first segment. The treehopper insect (above) is somewhat of an exception. In addition to having wings on its second segment, the treehopper’s first segment has an ornate helmet that resembles a set of thorns, which a recent study has found to be a modified, fused pair of “wings.” The thorn-like structure helps to camouflage the treehopper in tree branches, thus reducing its risk of predation. Explain how changes in gene regulation could have led to the evolution of such a structure

Contrast the organizations of the rRNA gene family and the globin gene families. For each, explain how the existence of a family of genes benefits the organism.

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