A kinetochore has been compared to a coupling device that connects a motor to the cargo that it moves. Explain.

Spindle fibers have microtubules; these microtubules have plus and minus ends. The plus end is present at the equator, while the minus end is present at the poles of the cells.

These help in the movement of the spindle chromosome linked to the kinetochore.

The kinetochores are mainly formed of protein particles. There are two kinetochores on the chromosome placed in the opposite direction.

Spindle microtubules join the kinetochore at the prometaphase. Species to species, the kinetochore number differs.

The kinetochore microtubules help in the movement of the chromosomes. The chromosomes initiate traveling to the pole side from where the microtubules extend. This movement sometimes stops when the microtubules join from the opposite pole to link with the kinetochore.

In the next step, there is a tug of war. The chromosome starts moving in the opposite direction, and it gets settled in the midline of the cell called the metaphase plate.