Interphase chromosomes appear to be attached to the nuclear lamina and perhaps also the nuclear matrix. Describe these two structures. See Figure 6.9 and the associated text.

Short Answer

Expert verified

A nuclear lamina is a network of intermediate filaments present against the inner surface of the nuclear envelope. A nuclear matrix is a network of protein fibers that forms the nucleus skeleton.

Step by step solution

01

Nucleus

The nucleus is the most prominent cell organelle when viewed through a microscope. The nuclear envelope surrounds it. A nuclear envelope is a complex structure that consists of an inner and outer membrane. A perinuclear space separates both the membranes.

The cell organelle stores the genetic information of the cell. It is also called the control center of the cell.

02

Nuclear lamina

A network of filaments is found lying against the inner membrane of the envelope. These are referred to as nuclear lamina, which are composed of laminins.The nuclear lamina is known to maintain the shape of the nucleus as it provides mechanical support to the nuclear envelope.

Nuclear lamina serves as the site of attachment for chromatin fibers. It also plays an integral role in the activities of the nucleus, such as cell cycle regulation, DNA replication, gene transcription, and many more.

03

Nuclear matrix

A network of fibers that form the skeleton of the nucleus is called a nuclear matrix.They are present in the nucleoplasm of the nucleus and are analogous to the cytoskeleton of the cell.

The nuclear matrix includes nuclear lamina, nuclear pores, and ribonucleoprotein network. It is observed as protein fibers extending from the interior of the nucleus.

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Most popular questions from this chapter

A biochemist isolates, purifies, and combines in a test tube a variety of molecules needed for DNA replication. When she adds some DNA to the mixture, replication occurs, but each DNA molecule consists of a normal strand paired with numerous segments of DNA a few hundred nucleotides long. What has she probably left out of the mixture?

  1. DNA polymerase
  2. DNA ligase
  3. Okazaki fragments
  4. primase

Given a polynucleotide sequence such as GAATTC. Explain what further information you would need in order to identify which is the 5’ end. (See Figure 16.5)

E.coli grown on a 15N medium is transferred to a 14N medium and allowed to grow for two more generations (two rounds of DNA replication). DNA extracted from these cells is centrifuged. What density distribution of DNA would you expect in this experiment?

  1. one high-density and one low-density band
  2. one intermediate density band
  3. one high density and one intermediate-density band
  4. one low-density and one intermediate-density band

Although the proteins that cause the E.coli chromosome to the coil are not histones, what property would you expect them to share with histones, given their ability to bind to DNA (see Figure 5.14)?

In his work with pneumonia-causing bacteria and mice, Griffith found that

  1. the protein coat from pathogenic cells was able to transform non-pathogenic cells.
  2. heat-killed pathogenic cells caused pneumonia.
  3. some substances from pathogenic cells were transferred to non-pathogenic cells, making them pathogenic.
  4. the polysaccharide coat of bacteria caused pneumonia.
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