Chapter 15: Problem 8
What is meant by a conditional mutation?
Chapter 15: Problem 8
What is meant by a conditional mutation?
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Get started for freeSuppose you are studying a DNA repair system, such as the nucleotide excision repair in vitro. By mistake, you add DNA ligase from a tube that has already expired. What would be the result?
What is a spontaneous mutation, and why are spontaneous mutations rare?
Acridine dyes induce frameshift mutations. Why are frameshift mutations likely to be more detrimental than point mutations, in which a single pyrimidine or purine has been substituted?
In maize, a \(D s\) or \(A c\) transposon can cause mutations in genes at or near the site of transposon insertion. It is possible for these elements to transpose away from their original site, causing a reversion of the mutant phenotype. In some cases, however, even more severe phenotypes appear, due to events at or near the mutant allele. What might be happening to the transposon or the nearby gene to create more severe mutations?
What genetic defects result in the disorder xeroderma pigmentosum (XP) in humans? How do these defects create the phenotypes associated with the disorder?
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