Chapter 18: Problem 20
In Arabidopsis, flower development is controlled by sets of homeotic genes. How many classes of these genes are there, and what structures are formed by their individual and combined expression?
Chapter 18: Problem 20
In Arabidopsis, flower development is controlled by sets of homeotic genes. How many classes of these genes are there, and what structures are formed by their individual and combined expression?
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Get started for freeCarefully distinguish between the terms differentiation and determination. Which phenomenon occurs initially during development?
The apterous gene in Drosophila encodes a protein required for wing patterning and growth. It is also known to function in nerve development, fertility, and viability. When human and mouse genes whose protein products closely resemble apterous were used to generate transgenic Drosophila (RinconLimas et al. \(1999 .\) Proc. Nat. Acad. Sci. \([\mathrm{USA}] 96: 2165-2170\) ) the apterous mutant phenotype was rescued. In addition, the whole-body expression patterns in the transgenic Drosophila were similar to normal apterous. (a) What is meant by the term rescued in this context? (b) What do these results indicate about the molecular nature of development?
Distinguish between the syncytial blastoderm stage and the cellular blastoderm stage in Drosophila embryogenesis.
Dominguez et al. (2004) suggest that by studying genes that determine growth and tissue specification in the eye of Drosophila, much can be learned about human eye development. (a) What evidence suggests that genetic eye determinants in Drosophila are also found in humans? Include a discussion of orthologous genes in your answer. (b) What evidence indicates that the eyeless gene is part of a developmental network? (c) Are genetic networks likely to specify developmental processes in general? Explain fully and provide an example.
(a) What are maternal-effect genes? (b) When are gene products from these genes made, and where are they located? (c) What aspects of development do maternal-effect genes control? (d) What is the phenotype of maternal-effect mutations?
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