Chapter 25: Problem 28
List the barriers that prevent interbreeding and give an example of each.
Chapter 25: Problem 28
List the barriers that prevent interbreeding and give an example of each.
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Get started for freeA number of comparisons of nucleotide sequences among hominids and rodents indicate that inbreeding may have occurred more in hominid than in rodent ancestry. When an ancient population bottleneck leaving approximately 10,000 individuals occurred in humans, Knight (2005) and Bakewell (2007) both suggested that this event may have left early humans with a greater chance of genetic disease. Why would a population bottleneck influence the frequency of genetic disease?
Read the Chapter Concepts list on page \(681 .\) All these pertain to the principles of population genetics and the evolution of species. Write a short essay describing the roles of mutation, migration, and selection in bringing about speciation.
A form of dwarfism known as Ellis-van Creveld syndrome was first discovered in the late 1930 s, when Richard Ellis and Simon van Creveld shared a train compartment on the way to a pediatrics meeting. In the course of conversation, they discovered that they each had a patient with this syndrome. They published a description of the syndrome in \(1940 .\) Affected individuals have a short-limbed form of dwarfism and often have defects of the lips and teeth, and polydactyly (extra fingers. The largest pedigree for the condition was reported in an Old Order Amish population in eastern Pennsylvania by Victor McKusick and his colleagues (1964). In that community, about 5 per 1000 births are affected, and in the population of \(8000,\) the observed frequency is 2 per \(1000 .\) All affected individuals have unaffected parents, and all affected cases can trace their ancestry to Samuel King and his wife, who arrived in the area in \(1774 .\) It is known that neither King nor his wife was affected with the disorder. There are no cases of the disorder in other Amish communities, such as those in Ohio or Indiana. (a) From the information provided, derive the most likely mode of inheritance of this disorder. Using the HardyWeinberg law, calculate the frequency of the mutant allele in the population and the frequency of heterozygotes, assuming Hardy-Weinberg conditions. (b) What is the most likely explanation for the high frequency of the disorder in the Pennsylvania Amish community and its absence in other Amish communities?
The ability to taste the compound PTC is controlled by a dominant allele \(T,\) while individuals homozygous for the recessive allele \(t\) are unable to taste PTC. In a genetics class of 125 students, 88 can taste \(\mathrm{PTC}\) and 37 cannot. Calculate the frequency of the \(T\) and \(t\) alleles and the frequency of the genotypes in this population.
In a population that meets the Hardy-Weinberg equilibrium assumptions, \(81 \%\) of the individuals are homozygous for a recessive allele. What percentage of the individuals would be expected to be heterozygous for this locus in the next generation?
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