Chapter 3: Problem 11
What is the basis for homology among chromosomes?
Chapter 3: Problem 11
What is the basis for homology among chromosomes?
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Get started for freeDentinogenesis imperfecta is a rare, autosomal, dominantly inherited disease of the teeth that occurs in about one in 8000 people (Witkop 1957 ). The teeth are somewhat brown in color, and the crowns wear down rapidly. Assume that a male with dentinogenesis imperfecta and no family history of the disease marries a woman with normal teeth. What is the probability that (a) their first child will have dentinogenesis imperfecta? (b) their first two children will have dentinogenesis imperfecta? (c) their first child will be a girl with dentinogenesis imperfecta?
Galactosemia is a rare recessive disorder caused by the deficiency of galactose- 1 -phosphate uridylyltransferase, leading to the accumulation of toxic levels of galactitol in the blood. It leads to a \(75 \%\) mortality rate in infants as infants cannot metabolize galactose from breast milk. In many countries, newborns are given a heel prick test to measure the levels of metabolic enzymes. As a genetic counselor, how would you explain to a couple whose baby has tested positive for galactosemia where the disease has come from?
The autosomal (not X-linked) gene for brachydactyly, short fingers, is dominant to normal finger length. Assume that a female with brachydactyly in the heterozygous condition is married to a man with normal fingers. What is the probability that (a) their first child will have brachydactyly? (b) their first two children will have brachydactyly? (c) their first child will be a brachydactylous girl?
The basis for rejecting any null hypothesis is arbitrary. The researcher can set more or less stringent standards by deciding to raise or lower the \(p\) value used to reject or not reject the hypothesis. In the case of the chi- square analysis of genetic crosses, would the use of a standard of \(p=0.10\) be more or less stringent about not rejecting the null hypothesis? Explain.
In a family of six children, where one grandparent on either side has red hair, what mathematical expression predicts the probability that two of the children have red hair?
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