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Chapter 3: Problem 22

Draw all possible conclusions concerning the mode of inheritance of the trait portrayed in each of the following limited pedigrees. (Each of the four cases is based on a different trait.) a. b. c. d.

Short Answer

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#Question# Analyze the given pedigrees and determine the mode of inheritance for each case. Provide evidence from the pedigree to support your conclusions.

Step by step solution

01

a. Analysis of the first pedigree

First, we need to carefully examine the pedigree and identify any patterns that emerge. Look for whether the trait appears equally in both males and females, or whether one gender is predominantly affected. Also, observe whether the trait is passed from one generation to the next or whether it skips any generation.
02

b. Analysis of the second pedigree

For the second pedigree, follow the same process as in the first. Identify any notable patterns between generations, affected individuals, and genders.
03

c. Analysis of the third pedigree

Analyze the third pedigree similarly to how the first two pedigrees were examined. Pay attention to any specific patterns or differences that can provide clues to the mode of inheritance.
04

d. Analysis of the fourth pedigree

Finally, look at the fourth pedigree and note any unusual patterns or similarities with the previous pedigrees. This will enable you to make educated guesses on the mode of inheritance.
05

e. Mode of inheritance conclusion for pedigree A

After closely analyzing pedigree A, deduce the most likely mode of inheritance for the trait. State the likely mode, making sure to include evidence from the pedigree to support your conclusion.
06

f. Mode of inheritance conclusion for pedigree B

Repeat the process for pedigree B, stating the mode of inheritance and providing evidence from the pedigree to back up your claim.
07

g. Mode of inheritance conclusion for pedigree C

In the same vein, establish the mode of inheritance for pedigree C and make sure to support your claim with observations from the pedigree.
08

h. Mode of inheritance conclusion for pedigree D

Finally, determine the mode of inheritance for pedigree D and provide evidence from the pedigree to justify your conclusion. Once you have deduced the mode of inheritance for each of the four cases, it's important to understand how these deductions can be useful in predicting the likelihood of the trait appearing in future generations or providing insights into other aspects of genetic inheritance.

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Most popular questions from this chapter

The autosomal (not X-linked) gene for brachydactyly, short fingers, is dominant to normal finger length. Assume that a female with brachydactyly in the heterozygous condition is married to a man with normal fingers. What is the probability that (a) their first child will have brachydactyly? (b) their first two children will have brachydactyly? (c) their first child will be a brachydactylous girl?

Which of Mendel's postulates can only be demonstrated in crosses involving at least two pairs of traits? State the postulate.

Tay-Sachs disease (TSD) is an inborn error of metabolism that results in death, often by the age of \(2 .\) You are a genetic counselor interviewing a phenotypically normal couple who tell you the male had a female first cousin (on his father's side) who died from TSD and the female had a maternal uncle with TSD. There are no other known cases in either of the families, and none of the matings have been between related individuals. Assume that this trait is very rare. (a) Draw a pedigree of the families of this couple, showing the relevant individuals. (b) Calculate the probability that both the male and female are carriers for TSD. (c) What is the probability that neither of them is a carrier? (d) What is the probability that one of them is a carrier and the other is not? [Hint: The \(p\) values in (b), (c), and (d) should equal \(1 .]\)

In this chapter, we focused on the Mendelian postulates, probability, and pedigree analysis. We also considered some of the methods and reasoning by which these ideas, concepts, and techniques were developed. On the basis of these discussions, what answers would you propose to the following questions: (a) How was Mendel able to derive postulates concerning the behavior of "unit factors" during gamete formation, when he could not directly observe them? (b) How do we know whether an organism expressing a dominant trait is homozygous or heterozygous? (c) In analyzing genetic data, how do we know whether deviation from the expected ratio is due to chance rather than to another, independent factor? (d) since experimental crosses are not performed in humans, how do we know how traits are inherited?

A certain type of congenital deafness in humans is caused by a rare autosomal (not X-linked) dominant gene. (a) In a mating involving a deaf man and a deaf woman (both heterozygous), would you expect all the children to be deaf? Explain your answer. (b) In a mating involving a deaf man and a deaf woman (both heterozygous), could all the children have normal hearing? Explain your answer. (c) Another form of deafness is caused by a rare autosomal recessive gene. In a mating involving a deaf man and a deaf woman, could some of the children have normal hearing? Explain your answer.
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