Chapter 3: Problem 6
What advantages were provided by Mendel's choice of the garden pea in his experiments?
Chapter 3: Problem 6
What advantages were provided by Mendel's choice of the garden pea in his experiments?
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Get started for freeAlbinism, lack of pigmentation in humans, results from an autosomal recessive gene (a). Two parents with normal pigmentation have an albino child. (a) What is the probability that their next child will be albino? (b) What is the probability that their next child will be an albino girl? (c) What is the probability that their next three children will be albino?
In a family of six children, where one grandparent on either side has red hair, what mathematical expression predicts the probability that two of the children have red hair?
In assessing data that fell into two phenotypic classes, a geneticist observed values of \(250: 150 .\) She decided to perform a \(\chi^{2}\) analysis by using the following two different null hypotheses: (a) the data fit a 3: 1 ratio, and (b) the data fit a 1: 1 ratio. Calculate the \(\chi^{2}\) values for each hypothesis. What can be concluded about each hypothesis?
Two true-breeding pea plants were crossed. One parent is round, terminal, violet, constricted, while the other expresses the respective contrasting phenotypes of wrinkled, axial, white, full. The four pairs of contrasting traits are controlled by four genes, each located on a separate chromosome. In the \(\mathrm{F}_{1}\) only round, axial, violet, and full were expressed. In the \(\mathrm{F}_{2},\) all possible combinations of these traits were expressed in ratios consistent with Mendelian inheritance. (a) What conclusion about the inheritance of the traits can be drawn based on the \(\mathrm{F}_{1}\) results? (b) In the \(\mathrm{F}_{2}\) results, which phenotype appeared most frequently? Write a mathematical expression that predicts the probability of occurrence of this phenotype. (c) Which \(\mathrm{F}_{2}\) phenotype is expected to occur least frequently? Write a mathematical expression that predicts this probability. (d) In the \(F_{2}\) generation, how often is either of the \(P_{1}\) phenotypes likely to occur? (e) If the \(F_{1}\) plants were testcrossed, how many different phenotypes would be produced? How does this number compare with the number of different phenotypes in the \(\mathrm{F}_{2}\) generation just discussed?
Tay-Sachs disease (TSD) is an inborn error of metabolism that results in death, often by the age of \(2 .\) You are a genetic counselor interviewing a phenotypically normal couple who tell you the male had a female first cousin (on his father's side) who died from TSD and the female had a maternal uncle with TSD. There are no other known cases in either of the families, and none of the matings have been between related individuals. Assume that this trait is very rare. (a) Draw a pedigree of the families of this couple, showing the relevant individuals. (b) Calculate the probability that both the male and female are carriers for TSD. (c) What is the probability that neither of them is a carrier? (d) What is the probability that one of them is a carrier and the other is not? [Hint: The \(p\) values in (b), (c), and (d) should equal \(1 .]\)
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