Chapter 21: Problem 15
Describe how populations with substantial genetic differences can form. What is the role of natural selection?
Chapter 21: Problem 15
Describe how populations with substantial genetic differences can form. What is the role of natural selection?
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Get started for freeThe original source of new alleles, upon which selection operates, is mutation, a random event that occurs without regard to selectional value in the organism. Although many model organisms have been used to study mutational events in populations, some investigators have developed abiotic molecular models. Soll et al. (2006. Genetics 175:267-275) examined one such model to study the relationship between both deleterious and advantageous mutations and population size in a ligase molecule composed of RNA (a ribozyme). Soll found that the smaller the population of molecules, the more likely it was that not only deleterious mutations but also advantageous mutations would disappear. Why would population size influence the survival of both types of mutations (deleterious and advantageous) in populations?
The genetic difference between two Drosophila species, \(D\). heteroneura and \(D\). silvestris, as measured by nucleotide diversity, is about 1.8 percent. The difference between chimpanzees \((\)Pan troglodytes ) and humans (H. sapiens) is about the same, yet the latter species is classified in a different genera. In your opinion, is this valid? Explain why.
Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.
ConsiderapopulationinwhichthefrequencyofalleleAisp \(=0.7\) and thefrequencyofalleleais \(q=0.3\), andwheretheallelesarecodominant. What will be the allele frequencies after one generation if the following occurs? (a) \(w_{A A}=1, w_{A a}=0.9, w_{a a}=0.8\) (b) \(w_{A A}=1, w_{A a}=0.95, w_{a a}=0.9\) (c) \(w_{A A}=1, w_{A a}=0.99, w_{a a}=0.98\) (d) \(w_{A A}=0.8, w_{A a}=1, w_{a a}=0.8\)
What are the two groups of reproductive isolating mechanisms? Which of these is regarded as more efficient, and why?
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