Chapter 21: Problem 18
What are considered significant factors in maintaining the surprisingly high levels of genetic variation in natural populations?
Chapter 21: Problem 18
What are considered significant factors in maintaining the surprisingly high levels of genetic variation in natural populations?
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Get started for freeIn a population where only the total number of individuals wit the dominant phenotype is known, how can you calculate th percentage of carriers and homozygous recessives?
The original source of new alleles, upon which selection operates, is mutation, a random event that occurs without regard to selectional value in the organism. Although many model organisms have been used to study mutational events in populations, some investigators have developed abiotic molecular models. Soll et al. (2006. Genetics 175:267-275) examined one such model to study the relationship between both deleterious and advantageous mutations and population size in a ligase molecule composed of RNA (a ribozyme). Soll found that the smaller the population of molecules, the more likely it was that not only deleterious mutations but also advantageous mutations would disappear. Why would population size influence the survival of both types of mutations (deleterious and advantageous) in populations?
Describe how populations with substantial genetic differences can form. What is the role of natural selection?
What are the two groups of reproductive isolating mechanisms? Which of these is regarded as more efficient, and why?
A recent study examining the mutation rates of 5669 mammalian genes \((17,208\) sequences) indicates that, contrary to popular belief, mutation rates among lineages with vastly different generation lengths and physiological attributes are remarkably constant [Kumar, S., and Subramanian, S. \((2002) .\) Proc. Natl. Acad. Sci.USA99:803-808|.Theaveragerateisestimatedat12.2 \(\times 10^{-9}\) perbp per year. What is the significance of this finding in terms of mammalian evolution?
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