Chapter 11: Problem 14
What do SINE and LINE mean in terms of chromosome struc- ture? Why are they called "repetitive"?
Chapter 11: Problem 14
What do SINE and LINE mean in terms of chromosome struc- ture? Why are they called "repetitive"?
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Get started for freeWhat genetic process is occurring in a puff of a polytene chromosome?
While much remains to be learned about the role of nucleosomes and chromatin structure and function, recent research indicates that in vivo chemical modification of histones is associated with changes in gene activity. For example, Bernstein and others (2000. Proc. Natl. Acad. Sci. USA 97: 5340-5345) determined that acetylation of \(\mathrm{H} 3\) and \(\mathrm{H} 4\) is associated with 21.1 percent and 13.8 percent increase in yeast gene activity, respectively, and that yeast heterochromatin is hypomethylated relative to the genome average. Speculate on the significance of these findings in terms of nucleosome- -DNA interactions and gene activity.
A particular variant of the lambda bacteriophage has a DNA double-stranded genome of 51,365 base pairs. How long would this DNA be?
Supercoiled DNA is slightly unwound compared to relaxed DNA and this enables it to assume a more compact structure with enhanced physical stability. Describe the enzymes that control the number of supercoils present in the \(E\) coli chromosome. How much would you have to reduce the linking number to increase the number of supercoils by five?
Define satellite DNA. Describe where it is found in the genome of eukaryotes and its role as part of chromosomes.
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