Chapter 5: Problem 5
Distinguish between (a) the concepts of sexual differentiation and sex determination and (b) Protenor and Lygaeus modes of sex determination.
Chapter 5: Problem 5
Distinguish between (a) the concepts of sexual differentiation and sex determination and (b) Protenor and Lygaeus modes of sex determination.
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Get started for freeHow do mammals, including humans, solve the "dosage prob- lem" caused by the presence of an \(\mathrm{X}\) and \(\mathrm{Y}\) chromosome in one sex and two X chromosomes in the other sex?
Under what circumstances can a male cat exhibit a tortoiseshell coat pattern?
A group of scientists developing an XX zygote in vitro are curious to see the impact of certain chemicals on the development of the said organism. They incubate the zygote with the help of testosterone and some transcription factors, which are usually produced by the activity of the Y chromosome. They discover that the zygote develops into a sterile female with masculinized reproductive organs. Explain why this happens.
In this chapter, we have focused on sex differentiation, sex chro- mosomes, and genetic mechanisms involved in sex determination. At the same time, we found many opportunities to consider the methods and reasoning by which much of this information was acquired. From the explanations given in the chapter, you should answer the following fundamental questions: (a) How do we know that in humans the X chromosomes play no role in sex determination, while the Y chromosome causes maleness and its absence causes femaleness? (b) How did we originally (in the late 1940 s) analyze the sex ratio at conception in humans, and how has our approach to studying this issue changed in \(2015 ?\) (c) How do we know that \(X\) chromosomal inactivation of either the paternal or maternal homolog is a random event during early development in mammalian females? (d) How do we know that Drosophila utilizes a different sexdetermination mechanism than mammals, even though it has the same sex-chromosome compositions in males and females?
It is believed that any male-determining genes contained on the Y chromosome in humans are not located in the limited region that synapses with the X chromosome during meiosis. What might be the outcome if such genes were located in this region?
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