Phenotypically wild \(\mathrm{F}_{1}\) female Drosophila, whose mothers had light eyes (It) and fathers had straw (stw) bristles, produced the following offspring when crossed with homozygous light-straw males:$$\begin{array}{lc} \text { Phenotype } & \text { Number } \\ \hline \text { light-straw } & 22 \\ \text { wild } & 18 \\ \text { light } & 990 \\ \text { straw } & \frac{970}{2000} \end{array}$$ Compute the map distance between the light and straw loci.

Short Answer

Expert verified
Answer: The approximate map distance between the light and straw loci in Drosophila is 48 centimorgans (cM).

Step by step solution

01

Identify the parental phenotypes

The F1 females are phenotypically wild and have mothers with light eyes (It) and fathers with straw (stw) bristles, so their genotype can be represented as It+ st+ / It stw. The homozygous light-straw males have a genotype of It stw / It stw. The phenotypes of the offspring resulting from this cross will help us calculate the recombination frequency.
02

Identify recombinant offspring

The recombinant offspring are those that have a phenotype different from the parental phenotypes (it's the result of a crossover event). In this case, light and straw are the recombinant phenotypes with frequencies of 990 and 970/2000 respectively.
03

Calculate the recombination frequency

The recombination frequency can be calculated as the ratio of the sum of the numbers of recombinant offspring to the total number of offspring. In this case, the recombination frequency is: Recombination frequency = (number of light offspring + number of straw offspring) / total number of offspring Recombination frequency = (990 + (970/2000)) / (22 + 18 + 990 + (970/2000))
04

Compute the map distance

The map distance in centimorgans (cM) is found by multiplying the recombination frequency by 100. So, Map distance = recombination frequency * 100 First, let's calculate the recombination frequency: Recombination frequency = (990 + (970/2000)) / (22 + 18 + 990 + (970/2000)) Recombination frequency ≈ 0.48 Now we can compute the map distance: Map distance = 0.48 * 100 Map distance ≈ 48 cM The map distance between the light and straw loci in Drosophila is approximately 48 centimorgans (cM).

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Most popular questions from this chapter

Why does more crossing over occur between two distantly linked genes than between two genes that are very close together on the same chromosome?

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