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Chapter 9: Problem 13

Draw the chemical structure of a dinucleotide composed of \(A\) and G. Opposite this structure, draw the dinucleotide composed of \(\mathrm{T}\) and \(\mathrm{C}\) in an antiparallel (or upside-down) fashion. Form the possible hydrogen bonds.

Short Answer

Expert verified
Question: Draw the chemical structure of a dinucleotide composed of Adenine (A) and Guanine (G) and another dinucleotide composed of Thymine (T) and Cytosine (C) in an antiparallel fashion. Show the hydrogen bonds that form between these two dinucleotides.

Step by step solution

01

Draw Adenine (A) and Guanine (G)

Draw Adenine (A) on the left and Guanine (G) on the right, with the sugar-phosphate backbone connecting them. The sugar molecules should be drawn with a pentagonal shape, and the phosphate groups should be indicated with the letter P inside a circle.
02

Draw Thymine (T) and Cytosine (C)

Now, draw Thymine (T) underneath Guanine (G) and Cytosine (C) underneath Adenine (A). Make sure to draw them in an antiparallel fashion by flipping them upside-down in relation to the first dinucleotide. Connect T and C with their sugar-phosphate backbone as well.
03

Form hydrogen bonds between Adenine (A) and Thymine (T)

Next, represent the hydrogen bonds between Adenine (A) and Thymine (T) by drawing two dashed lines between them. Adenine forms two hydrogen bonds with Thymine.
04

Form hydrogen bonds between Guanine (G) and Cytosine (C)

Lastly, form the hydrogen bonds between Guanine (G) and Cytosine (C) by drawing three dashed lines between them. Guanine forms three hydrogen bonds with Cytosine. Now you have successfully drawn the dinucleotide structure composed of A and G and the dinucleotide composed of T and C in an antiparallel fashion with the possible hydrogen bonds formed between them.

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Most popular questions from this chapter

Assume that you are interested in separating short \((25-40\) nucleotides) DNA molecules from a pool of longer molecules in the \(900-1000\) nucleotide range. You have two recipes for making your polyacrylamide gels; one recipe uses 12 percent acrylamide and would be considered a "hard gel," while the other uses 4 percent acrylamide and would be considered a loose gel. Which recipe would you consider using and why?

Why were \(^{32} \mathrm{P}\) and \(^{35} \mathrm{S}\) chosen in the Hershey-Chase experiment? Discuss the rationale and conclusions of this experiment.

What evidence did Watson and Crick have at their disposal in \(1953 ?\) What was their approach in arriving at the structure of DNA?

What are the three major types of RNA molecules? How is each related to the concept of information flow?

Discuss the reasons why proteins were generally favored over DNA as the genetic material before \(1940 .\) What was the role of the tetranucleotide hypothesis in this controversy?
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