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Chapter 21: Q12CP (page 746)

Describe the two general metabolic fates of the carbon skeletons of amino acids.

Short Answer

Expert verified

Two general metabolic fates of the carbon skeletons of amino acids are glucogenic amino acids and ketogenic amino acids.

Step by step solution

01

Degradation of amino acids.

Amino acids are degraded to compounds that can be metabolized to CO2 and H2O or used in gluconeogenesis. The amino acids can be divided into groups based on their catabolic pathways.

02

Step 2: Glucogenic amino acids.

The glucogenic amino acid is degraded to pyruvate,α-ketoglutarate, succinyl-CoA, fumarate, or oxaloacetateand is a glucose precursor.

03

Step 3: Ketogenic amino acids.  

The ketogenic amino acids are broken down to acetyl-CoA or acetoacetate and can be converted to fatty acids or ketone bodies.

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