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Chapter 25: Q5CP (page 897)

What is it important for DNA polymerase 1 to have three sites?

Short Answer

Expert verified

DNA polymerase enzyme synthesis a new complementary strand of DNA by

Incorporating SNMP sequentially in the S¹ to 3¹ directions.

Step by step solution

01

DNA polymerase 1

It is an enzyme that is responsible for forming new copies of DNA in the form of nucleic

acid molecules.

02

Three active sites of DNA polymerase

Polymerase 1provides three distinct catalyticactivities

3¹ to exonuclease,

S¹ to 3¹ exonucleases,

And S¹ to 3¹ polymerase activity.

Thus, DNA polymerase 1 needs to have three sites.

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Most popular questions from this chapter

Describe different kinds of mutations.

What is the function of the pre-replication complex?

Since mammalian DNA contains roughly 25% thymine residues, why do mammalian cells need a thymine-DNA glycosylase

What are the symptoms of defective nucleotaide excision the mismatch repair?

A certain mutant DNA polymerase is error-prone, tending to incorporate C opposite a template A. When such a DNA polymerase replicates a segment of DNA containing an A · T base pair, what will be the DNA composition in the daughter cells after (a) one and (b) two rounds of cell division? Assume that DNA repair does not occur.

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