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Chapter 18: Q20P (page 627)

What thermodynamic force drives the transport of ADP and Pi into the mitochondrial matrix for ATP synthesis?

Short Answer

Expert verified

The protonmotive force drives the transport of ADP and Pi into the mitochondrial matrix for ATP synthesis.

Step by step solution

01

Protonmotive force

The proton motive force (PMF) is the force that encourages protons to migrate downhill in the electrochemical potential across membranes. Because of the electrical and pH discrepancyes across the membrane, the respiratory chain creates a protonmotive force (PMF).

02

The thermodynamic force that cause ATP synthesis

The electrochemical gradient generates free energy, which is used to power ATP production. An ATPase catalyzes the condensation of Pi with ADP, resulting in the synthesis of ATP, as a result of this force.

Hence, since the transport systems for ADP and Pi both dissipate the proton gradient, the transport of both ADP and Pi is driven by the free energy of the electrochemical proton gradient.

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Most popular questions from this chapter

Activated neutrophils and macrophages (types of white blood cells) fight invading bacteria by releasing superoxide. These cells contain an NADPH oxidase that catalyzes the reaction

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For the mitochondrial membrane described in Problem 31, how many protons must be transported to provide enough free energy for the synthesis of 1 mol of ATP (assuming standard biochemical conditions)?

For the experimental system described in Problem 17, and assuming all the substrates for oxidative phosphorylation are present in excess, does ATP synthesis increase or decrease with an increase in the pH of the fluid in which the submitochondrial particles are suspended?
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