Compare structure-based drug design and combinatorial chemistry as tools for developing drug candidates.

Drug design is the process of coming up with novel treatments based on a biological target's information. At its most basic level, drug design creates molecules that are complementary in form and charge to the molecular targetwith which they interact and bind.

Direct drug design refers to drug design based on the enzyme's structure and the drug candidate. It is also known as rational drug design. This approach depends on X-Ray Crystallography or NMR Spectroscopy,which helps determine molecules' macromolecular structure.Thus, it helps to reduce the number of molecules that must be manufactured in a drug development procedure.

The structure of a receptor or enzyme in association with a drug candidate is used in structure-based drug design (also known as rational drug design) to aid the development of a more effective molecule.

A collection of chemical synthesis processes is referred to as combinatorial chemistry. These approaches make it possible to make many chemicals in one step with the help of high-throughput screening techniques.

High-throughput screening (HTS) is adrug discovery approach that involves the automated testing of many chemical or biological substances for a specific biological target, such as through binding tests.