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Chapter 20: Q21P (page 716)

On what carbon atoms does the 14CO2, used to synthesize malonyl-CoA from acetyl-CoA appear in palmitate?

Short Answer

Expert verified

The 14C label does not appear in the palmitate.

Step by step solution

01

Palmitate

A fatty acid with a 16-carbon chain is called palmitic acid or hexadecanoic acid in IUPAC nomenclature.It is the most prevalent saturated fatty acid in all living things, including humans, animals, and plants.

02

Beta-ketoacyl-ACP-synthase

The enzyme β-ketoacyl-ACP synthase is involved in the production of fatty acids. This enzyme uses malonyl-CoA as a carbon source to elongate the ACP-bound acyl species.

03

Step 2: Carbon atoms on which 14CO2 used to synthesize malonyl-CoA

The acetyl group from ACP is transferred to the Cys residue by β-ketoacyl-ACP synthase. The malonyl-ACP is then decarboxylated in the second phase, resulting in the loss of 14C labeled CO2.

As a result, the 14C label does not appear in the palmitate.

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Most popular questions from this chapter

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