Chapter 20: Q26CP (page 697)
Question: Where are membrane lipids synthesized?
Short Answer
The synthesis of the membrane lipids takes place in the endoplasmic reticulum membrane, from where they are transported to their destination.
Chapter 20: Q26CP (page 697)
Question: Where are membrane lipids synthesized?
The synthesis of the membrane lipids takes place in the endoplasmic reticulum membrane, from where they are transported to their destination.
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Hypercholesterolemic individuals taking statins are sometimes advised to take supplements of coenzyme Q. Explain
Why are the symptoms of carnitine palmitoyl transferase|| deficiency more severe during fasting?
Digestion of plant materials generates phytanate (derived from chlorophyll molecules; Fig. 19-2).
(a) Explain why phytanate cannot be catabolized by oxidation.
(b) Instead, phytanate is linked to CoA, then a peroxisomaldioxygenase converts phytanoyl-CoA to hydroxyphytanoyl-CoA. Draw the structure of this intermediate.
(c) 2-Hydroxyphytanoyl-CoA lyase generates an aldehyde (pristanal) and formyl-CoA. Draw the structure of pristanal.
Answer
Compare the energy cost, in ATP equivalents, of synthesizing stearate from mitochondrial acetyl-CoA to the energy recovered by degrading stearate to acetyl-CoA.
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