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Chapter 9: Q33P (page 291)

Question: Predict the effect of a mutation in signal peptidase that narrows its specificity so that it cleaves only between two Leu residues.

Short Answer

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Answer

Theproteins fold abnormally and function abnormally.

Step by step solution

01

Mutation

Mutation is a term used to describe changes in DNA sequencesthat have negative consequences for an organism. Errors in DNA replication cause this condition. Other forms of DNA damage, such as exposure to radiation or toxins, can also result in this condition. It can also happen as a result of replication mistakes or when mobile genetic elementsinduce the insertion or deletion of segments of DNA.

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Most popular questions from this chapter

Question: E. coli outer membranes include a component known as Lipid A, shown here. Identify its saccharide and fatty acid constituents.

Question: Identify a 20-residue segment that could form a transmembrane α helix in this protein sequence (from the mosquito Orco).

Why are biological membranes asymmetrical?

What are the two types of secondary structures that occur in transmembrane proteins?

Question: Brief Exercises Brief, online bioinformatics homework exercises can be found in WileyPLUS Learning Space.

Exercise 1 Drawing and Naming Fatty Acids

Exercise 2 Introduction to Lipidomics

Exercise 3 Properties of Membrane Proteins
See all solutions

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