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Chapter 22: Q12CP (page 790)

Why is AMPK called the cell’s fuel gauge?

Short Answer

Expert verified

AMPK is the cell’s fuel gauge because it regulates the generation and conservation of the adenosine triphosphate (ATP).

Step by step solution

01

AMPK

AMPK, known as “Activated protein kinase,” is a α,β,γheterotrimer found in all eukaryotic organism example: yeast, humans, etc., and its domain is phosphorylated for activity.

02

Step 2: AMPK cell’s fuel gauge

Activated protein kinase (AMPK) regulates metabolic homeostasis because it generates the adenosine triphosphate (ATP) by activating the metabolic breakdown pathways and conserves ATP for more vital/important processes by inhibiting biosynthetic pathways therefore known as the cell’s fuel gauge.

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Most popular questions from this chapter

The passive glucose transporter named GLUT1 (Fig. 10-13) is present in the membranes of many cells, but not in the liver. Instead, liver cells express the GLUT2 transporter, which exhibits different transport kinetics. Given what you know about the role of the liver in buffering blood glucose, compare the KMvalues of GLUT1 and GLUT2.

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Use the results of Problem 5 to explain why a deficiency of GLUT2 produces symptoms resembling those of Type 1 glycogen storage disease (Box 16-2).

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