Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 23: Q9CP (page 820)

Describe the production of dNTPs from their corresponding NDPs.

Short Answer

Expert verified

The production of dNTP from NDP is as follows:

NDP→ribonucleotidereductasedNDPdNDP+ATP→kinasedNTP+ADP

Step by step solution

01

Nucleotides

The nucleotides are the components of the nucleic acids, including ribonucleic acid (RNA) and deoxyribonucleic acid (DNA).It contains sugar moiety, including ribose sugar and deoxyribose sugar, nitrogenous base, and the phosphate group.

02

Production of dNDP from NDP

The deoxyribonucleoside diphosphate (dNDP) is produced from the ribonucleoside diphosphate (NDP) by the ribonucleotide reductases.

NDP→ribonucleotidereductasedNDP

03

Production of dNTP from dNDP

The deoxyribonucleotide triphosphate (dNTP) can be produced by the phosphorylation of the dNDP, which is catalyzed by the kinase enzyme.

dNDP+ATP→kinasedNTP+ADP

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

6-Mercaptopurine (Box 23-2), after its conversion to the corresponding nucleotide through salvage reactions, is a potent competitive inhibitor of IMP in the pathways for AMP and GMP biosynthesis. It is therefore a clinically useful anticancer agent. The chemotherapeutic effectiveness of 6-mercaptopurine is enhanced when it is administered with allopurinol. Explain the mechanism of this enhancement.

List all the enzymes of nucleotide biosynthesis that use glutamine as an amino group donor.

The compound shown here is being tested as an anticancer agent.

(a) Explain why it inhibits CTP production.

(b) Explain why it also inhibits phospholipid synthesis.

Describe the reactions catalyzed by nucleoside phosphorylase, adenosine deaminase, and xanthine oxidase.

Describe how the fumarate produced by the purine nucleotide cycle could be catabolized to CO2.
See all solutions

Recommended explanations on Biology Textbooks

Cell Communication

Read Explanation

Communicable Diseases

Read Explanation

Heredity

Read Explanation

Ecosystems

Read Explanation

Plant Biology

Read Explanation

Control of Gene Expression

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free