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Chapter 6: Q13. (page 158)

Describe some of the common protein structural motifs.

Short Answer

Expert verified

Some common structural motifs in globular proteins areβαβmotif,βhairpinmotifs,ααmotifs,greekkeymotif,etc.

Step by step solution

01

Protein structural motifs

Combining the secondary structural elements, such as α helices and β sheets, in a globular protein forms the supersecondary structuresormotifs of the protein.

02

βαβ motif

βαβ motifis the most common supersecondary structure, where an α helix joins two parallel β sheets.

03

β hairpin

β hairpinis another common supersecondary structure, where relatively tight reverse turns join the antiparallel β sheets.

04

αα motif

In this supersecondary structure, two successive antiparallel α helices connectwith their axis inclined. This connection allows the energetically favorable interactions in a coiled coil conformation.

05

Greek key motifs

In a greek key motif, a β hairpin folds over to form 4-stranded antiparallel β sheets.

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