Chapter 6: Q25P (page 178)

Question: Explain why Pro residues can occupy the N-terminal turn of an $α$ helix.

Short Answer

Expert verified

Due to Proline Pro residues can occupy the N-terminal turn of an $α$ helix as they do not clash with other residues.-

Step by step solution

Concept Introduction

Every backbone $C = O$ group in the right-hand helix shape known as the alpha helix ( $α$ -helix) forms a hydrogen bond with the backbone group of the amino acid that is four residues earlier in the protein sequence.

Pro Residues occupying N-terminal turn of Helix

The pyrrolidine ring of Pro in the interior of an $α$ helix sterically interferes with the residue one turn towards the N-terminus. Pro residues in the N-terminal turn of an helix do not clash with other residues so it can occupy the N-terminal turn of an helix.

Therefore, the major reason is Proline.

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Question: Explain why Pro residues can occupy the N-terminal turn of an $α$ helix.

Short Answer

Step by step solution

Concept Introduction

Pro Residues occupying N-terminal turn of Helix

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Question: Explain why Pro residues can occupy the N-terminal turn of anαhelix.

Short Answer

Step by step solution

Concept Introduction

Pro Residues occupying N-terminal turn of Helix

One App. One Place for Learning.

Most popular questions from this chapter

Recommended explanations on Biology Textbooks

Genetic Information

Biological Molecules

Biological Structures

Heredity

Cellular Energetics

Plant Biology

Study anywhere. Anytime. Across all devices.

Question: Explain why Pro residues can occupy the N-terminal turn of an $α$ helix.