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Chapter 28: 7CP (page 1052)
What is the regulatory advantage of arranging genes in opera’s?
A gene is an expression of a nucleotide in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein.
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Describe the steps of RNA interference.
What is the relationship between genome size and gene number in different organisms?
Question Proliferation and diff erentiation of T and B lymphocytes during animmune response are mediated by signaling that leads to phosphorylation of a protein called IκB. Unphosphorylated IκB binds to and inhibitsthe transcription factor NF-κB. Phosphorylated IκB releases NF-κB andis then ubiquitinated and degraded by a proteasome. (a) Explain whythis mechanism for activating NF-κB allows rapid changes in gene expression. (b) Explain why directly phosphorylating NF-κB might notbe an eff ective mechanism for altering gene expression. (c) A proteinproduced by Yersinia pestis (the bacterium that causes plague) removesthe ubiquitin molecules from IκB. How would this aff ect the immune response to the Yersinia infection?
Why do coli cells with a defective lac Z gene fail to show galactoside permease activity after the addition of lactose in the absence of glucose?
Describe how histone modify cations can affect the structure of nucleosomes and the function of transcription factors.
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