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Chapter 26: Q19P (page 980)
In what ways do histone gene transcripts differ from transcripts of other vertebrate protein-coding genes?
Histone mRNAs are not spliced like those of other protein-coding genes because they lack introns.
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Human cells contain a protein that binds to the triphosphate groups of RNA. Explain why this protein would be part of the defense against viral infection.
Question: Collisions between DNA polymerase and a slower-moving RNA polymerase using the same template strand may be responsible for the observation that leading strand synthesis in bacteria is discontinuous in vivo. Draw a diagram to show how DNA synthesis that has been halted after the DNA polymerase–RNA polymerase collision can resume using the RNA transcript as a primer.
Design a six-residue nucleic acid probe that would hybridize with the greatest number of E. coli gene promoters.
The antibiotic cordycepin inhibits bacterial RNA synthesis.
A eukaryotic ribosome contains four different rRNA molecules and ∼82 different proteins. Why does a cell contain many more copies of the rRNA genes than the ribosomal protein genes?
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