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Chapter 1: Problem 109

The client is taking prednisone \(7.5 \mathrm{mg}\) po each morning to treat his systemic lupus errythymatosis. Which statement best explains the reason for taking the prednisone in the morning? A. There is less chance of forgetting the medication if taken in the morning. B. There will be less fluid retention if taken in the morning. C. Prednisone is absorbed best with the breakfast meal. D. Morning administration mimics the body's natural secretion of corticosteroid.

Short Answer

Expert verified
Answer: The best reason for taking prednisone in the morning is that the morning administration mimics the body's natural secretion of corticosteroid. This ensures better effectiveness and fewer side effects in the treatment of conditions like systemic lupus erythematosus.

Step by step solution

01

Understand Prednisone

Prednisone is a corticosteroid medication that helps to reduce inflammation and suppress the immune system. It is often prescribed for conditions like systemic lupus erythematosus, which causes inflammation in various parts of the body. For better results and fewer side effects, the timing of the medication is important.
02

Evaluate Option A

A. There is less chance of forgetting the medication if taken in the morning. While this may be true, it's not the primary reason for taking prednisone in the morning. There is a more specific biological reason related to corticosteroid secretion.
03

Evaluate Option B

B. There will be less fluid retention if taken in the morning. Although some medications may cause less fluid retention if taken in the morning, this is not the primary reason for taking prednisone specifically in the morning. We need to focus on the mechanism of action of the drug and its relation to the natural secretion of corticosteroids.
04

Evaluate Option C

C. Prednisone is absorbed best with the breakfast meal. The absorption of prednisone might be slightly better with a meal, but this is not the main reason for taking it in the morning. The key is to relate the drug administration to the natural secretion pattern of corticosteroids in the body.
05

Evaluate Option D

D. Morning administration mimics the body's natural secretion of corticosteroid. This is the correct answer. The body naturally secretes cortisol (a corticosteroid) in the morning, reaching its peak around 8 am. Taking prednisone in the morning mimics this natural secretion pattern, helping to minimize side effects and maximize the drug's effectiveness.
06

Conclusion

The best reason for taking prednisone in the morning is that the morning administration mimics the body's natural secretion of corticosteroid (Option D). This ensures better effectiveness and fewer side effects in the treatment of conditions like systemic lupus erythematosus.

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