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Chapter 15: Problem 19

ELR+ chemokines target which cell type? a. Monocytes and lymphocytes b. Neutrophils c. Progenitor cells b. Monocytes

Short Answer

Expert verified
Answer: b. Neutrophils

Step by step solution

01

Understand ELR+ chemokines

ELR+ chemokines are a group of chemotactic cytokines containing the amino acid motif 'ELR' (glutamic acid-leucine-arginine) in their sequence. They are involved in the recruitment and activation of immune cells during inflammation and infection.
02

Analyze the given options

We have four options given: a. Monocytes and lymphocytes b. Neutrophils c. Progenitor cells d. Monocytes We need to select the correct one based on the target cell type of ELR+ chemokines.
03

Determine ELR+ chemokines targets

ELR+ chemokines primarily target neutrophils, which are the first line of immune defense against infections. They help attract and activate neutrophils at the site of inflammation and infection. However, some ELR+ chemokines can also target other leukocytes like monocytes and lymphocytes.
04

Choose the correct answer

Based on this information, the primary target of ELR+ chemokines are neutrophils. Therefore, the correct answer is: b. Neutrophils

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