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Chapter 23: Problem 7

Which part is mostly degenerated in spinal cord in patients with HAM/TSP? a. Anterior column b. Lateral column c. Posterior column

Short Answer

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a. Anterior column b. Lateral column c. Posterior column Answer: b. Lateral column Explanation: HAM/TSP is a neurological disorder caused by the human T-cell lymphotropic virus type 1 (HTLV-1), which primarily affects the lateral column of the spinal cord. This degeneration results in motor and sensory problems, such as muscle weakness, spasticity, and difficulty with balance and coordination. The anterior and posterior columns are less impacted in this condition.

Step by step solution

01

Correct Answer

The correct answer is option b. Lateral column.
02

Explanation

The lateral column of the spinal cord is mainly affected in patients with HAM/TSP. The degeneration of the lateral column leads to motor and sensory problems, such as muscle weakness, spasticity, and difficulty with balance and coordination. The anterior and posterior columns are less affected in this condition.

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Most popular questions from this chapter

Which cytokine is mostly detected at degenerated spinal cord in HAM/TSP? a. TNF-alpha b. IL-1 beta c. IFN-gamma

Which level of spinal cord is predominantly affected in patients with HAM/TSP? a. cervical level b. thoracic level c. lumbar level

What are the reservoir cells of the infected HTLV-I? a. T cells b. \(\mathrm{B}\) cells c. Macrophages

Which adhesion molecules are mostly detected in the spinal cord of HAM/TSP? a. ICAM-1 b. VCAM-1 c. ICAM-1 and VCAM-1

What type of human leukocyte antigen (HLA) is regarded as the higher risk factor associated with HAM/TSP? a. HLA-A*02(+) b. HLA-Cw=08( \(+)\) c. HLA-DRB1*0101(+)
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