Herpes simplex virus-2 infection occurs predominantly in a. the elderly b. women c. homosexual men d. cancer patients e. sexually active adolescents

First, we need to go through each option and understand what they refer to: a. the elderly b. women c. homosexual men d. cancer patients e. sexually active adolescents

Next, let's briefly evaluate the available options based on what we know about Herpes simplex virus-2 infection: a) The elderly: While it's possible for HSV-2 infection to affect the elderly, it's not necessarily predominant in this group. b) Women: Women may be at a higher risk of contracting HSV-2 due to biological factors, which could make this a possible answer. c) Homosexual men: While homosexual men can get HSV-2, the infection is not predominantly observed in this group. d) Cancer patients: HSV-2 can affect anyone, including cancer patients, but it's not predominantly observed in this group. e) Sexually active adolescents: HSV-2 is a sexually transmitted infection, meaning that sexually active individuals are at a higher risk, and this includes sexually active adolescents.

After evaluating each of the available options, we can conclude that the most accurate answer is: b. Women This is due to the fact that women are at a higher risk of contracting HSV-2 due to certain biological factors, and thus the infection occurs predominantly in women.