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Chapter 24: Problem 6

Intravenous administration of acyclovir is most likely to cause a. anaphylactic shock b. renal toxicity c. liver toxicity d. bone marrow suppression e. cardiac arrhythmias

Short Answer

Expert verified
Answer: (b) Renal toxicity

Step by step solution

01

Understand acyclovir and its uses

Acyclovir is an antiviral medication commonly used to treat herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections. It can be administered in different ways, including intravenous (IV) infusion, which is the focus of this exercise.
02

Review possible side effects

(a) Anaphylactic shock: a severe allergic reaction that can be life-threatening. (b) Renal toxicity: damage to the kidneys due to toxicity. (c) Liver toxicity: damage to the liver due to toxicity. (d) Bone marrow suppression: decrease in the production of blood cells in the bone marrow. (e) Cardiac arrhythmias: irregular heartbeats or abnormal heart rhythms.
03

Research side effects of acyclovir

To determine the most likely side effect of intravenous acyclovir administration, we can review available literature on acyclovir and its side effects. Several research articles and drug information databases will confirm that renal toxicity is the main concern with IV administration of acyclovir.
04

Compare and select the most likely side effect

Based on the previous step, we know that renal toxicity is the most likely side effect of intravenous acyclovir administration. Although other side effects may be possible, research suggests that renal toxicity is the most common and relevant concern in this case. Therefore, the correct answer is (b) renal toxicity.

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Most popular questions from this chapter

Effective vaccines have been developed against which virus a. herpes simplex virus type 1 b. Japanese encephalitis virus c. rabies d. SV40

Which of the following viruses causes encephalitis only in newborn children? a. West Nile virus b. herpes simplex virus type I c. human cytomegalovirus d. varicella virus zoster e. all of the above

Which of the following best describes the mechanism of action of acyclovir? a. inhibition of reverse transcriptase. b. stimulation of viral interferon production c. inhibition of viral DNA polymerase d. inhibition of viral protein synthesis e. inhibition of de nove purine synthesis

Rabies virus contains a. a negative stranded RNA viral genome and humans contract it primarily from being bitten by a domestic dog. b. is only a problem in young children or older adults. c. can be effectively treated with anti-inflammatory agents. d. can only be grown in young mice.

Fill in the blanks _____ is a member of the Flaviviridae and has been spread by mosquitoes in North America.
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