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Chapter 33: Problem 10

Genomic convergence provides a. a method for greatly increasing the resolution of linkage peaks b. a method for using non-human primates to identify causative alleles c. an approach to prioritize candidates for further genetic study d. all of the above e. none of the above

Short Answer

Expert verified
Answer: c. an approach to prioritize candidates for further genetic study

Step by step solution

01

Analyze option a

Option a states that genomic convergence provides a method for greatly increasing the resolution of linkage peaks. Although genomic convergence can sometimes help in identifying candidate genes and increasing resolution, this doesn't encapsulate the entire concept of genomic convergence. Keep this option on hold and evaluate the remaining options.
02

Analyze option b

Option b states that genomic convergence provides a method for using non-human primates to identify causative alleles. Primates can be used as models in comparative genomics, but this is not the main focus of genomic convergence. Therefore, option b doesn't cover the entire concept of genomic convergence.
03

Analyze option c

Option c states that genomic convergence provides an approach to prioritize candidates for further genetic study. This is a more accurate description of the genomic convergence, as it involves converging evidence from multiple sources, such as genetic linkage, gene expression, and comparative genomics, to identify and prioritize candidate genes for further investigation.
04

Analyze option d

Option d suggests that genomic convergence includes all of the mentioned points (options a, b, and c). While options a and b may sometimes be involved, they are not the main focus of genomic convergence. Hence, option d is not the most accurate representation of the concept.
05

Analyze option e

Option e states that none of the given options represents the genomic convergence. However, we have found that option c is a more accurate description of genomic convergence.
06

Choose the correct answer

Based on the analysis, option c is the most appropriate description for genomic convergence, as it correctly represents the approach to prioritize candidates for further genetic study. Therefore, the correct answer is: c. an approach to prioritize candidates for further genetic study

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Most popular questions from this chapter

An advantage to using single nucleotide polymorphisms in genetic studies is that a. each marker is highly polymorphic b. they are common and distributed throughout the genome c. they are always within exons, and therefore cause a functional change d. all of the above e. none of the above

Huntington disease is an example of a dominantly inherited disease because a. two copies of the disease allele are needed to express the disease b. the disease locus is on the \(\mathrm{X}\) chromosome c. only one copy of the disease allele is needed to express the disease d. it exhibits classic anticipation e. it can only be inherited from an affected mother

Microsatellites a. are relatively highly polymorphic genetic markers b. can by amplified by polymerase chain reactions c. contain repeated elements d. all of the above e. none of the above

The genetics underlying multiple sclerosis are typical for a neurodegenerative disease in that a. concordance rates in monozygotic twins is higher than in dizygotic twins. b. linkage and association approaches have been used to identify likely candidates for a role in the disease c. there is an important environmental component to the disease d. all of the above e. none of the above

Allelic genetic association analyses may find positive associations because the a. allele causes the disease b. allele is in strong linkage disequilibrium with the disease allele c. result is a false positive d. all of the above e. none of the above
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