Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 44: Problem 13

A ligand utilized for in vivo imaging of reactive microglia via upregulated peripheral benzodiazepine receptors is a. CFT b. DA c. GTlb d. MPTP e. PK 1195

Short Answer

Expert verified
Answer: PK 1195

Step by step solution

01

Understand the terms involved

In this exercise, the terms you need to understand are: ligand, in vivo imaging, reactive microglia, peripheral benzodiazepine receptors, and the given options (CFT, DA, GTlb, MPTP, PK 1195). - Ligand: A molecule that binds to another (usually larger) molecule - In vivo imaging: Non-invasive observation of living organisms - Reactive microglia: Immune cells in the central nervous system that get activated in response to injury or disease - Peripheral benzodiazepine receptors (PBR): Proteins associated with the outer mitochondrial membrane, that play a role in various cellular processes
02

Eliminate the incorrect options

Now that we have an understanding of the key terms involved in the problem, we can eliminate the incorrect answer choices and list out the reasoning behind eliminating them. a. CFT: Cocaine analog that binds to the dopamine transporter and is not related to imaging reactive microglia b. DA: Dopamine is a neurotransmitter and is not associated with the peripheral benzodiazepine receptor c. GTlb: Not a known ligand associated with the imaging of reactive microglia or peripheral benzodiazepine receptors d. MPTP: A neurotoxin that induces Parkinson's-like symptoms but is not involved in imaging reactive microglia
03

Identify the correct answer

After eliminating the incorrect options, we are left with the following option: e. PK 1195: This ligand has been shown to selectively bind to the peripheral benzodiazepine receptors and can be used for in vivo imaging of reactive microglia. Therefore, the correct answer is option e. PK 1195.

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

IL-2/IL-2R interactions are found localized to a. \(\mathrm{T}\) cell-T cell interactions b. striatum c. frontal cortex d. cerebellum e. all of the above

An example of free radical modification of RNA is a. 8-hydroxyguanosine (8-OHG) b. 4-hydroxy-2-nonenal (HNE) c. 3-nitrotyrosine (NT) d. 8-hydroxy-2'-deoxyguanosine (8-OHdG)

The cellular target for immunotherapy that would be most beneficial to inhibit secondary neurodegeneration is the a. astrocyte b. neuron c. microglia d. oligodentrocyte

The possible mechanism by which glatiramer acetate functions is a. competition with myelin-basic protein (MBP) for binding to major histocompatibility complex (MHC) molecules b. competition of GA/MHC with MBP/MHC for binding to the T-cell receptor c. partial activation and tolerance induction of MBP-specific T cells d. induction of GA-reactive T-helper 2- (TH2)-like regulatory cells e. all of the above

One molecular marker of nitric oxide modification of proteins is a. 8-hydroxyguanosine (8-OHG) b. 4-hydroxy-2-nonenal (HNE) c. 3-nitrotyrosine (NT) d. 8-hydroxy-2'-deoxyguanosine (8-OHdG)
See all solutions

Recommended explanations on Biology Textbooks

Biological Molecules

Read Explanation

Ecological Levels

Read Explanation

Ecology

Read Explanation

Plant Biology

Read Explanation

Cell Communication

Read Explanation

Biological Organisms

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free