Chapter 14: Problem 9
As noted on page \(423,\) a true transition state can bind to an enzyme active site with a \(K_{\mathrm{T}}\) as low as \(7 \times 10^{-26} M .\) This is a remarkable number, with interesting consequences. Consider a hypothetical solution of an enzyme in equilibrium with a ligand that binds with a \(K_{\mathrm{D}}\) of \(10^{-27} M .\) If the concentration of free enzyme, \([\mathrm{E}],\) is equal to the concentration of the enzyme-ligand complex, [EL], what would \([\mathrm{L}],\) the concentration of free ligand, be? Calculate the volume of solution that would hold one molecule of free ligand at this concentration.
Short Answer
Step by step solution
Key Concepts
These are the key concepts you need to understand to accurately answer the question.