Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 24: Problem 92

Glutathione is a tripeptide found in most living cells. Partial hydrolysis yields Cys-Gly and Glu-Cys. What structures are possible for glutathione?

Short Answer

Expert verified
The possible structure for glutathione, based on the partial hydrolysis results (Cys-Gly and Glu-Cys), is Glu-Cys-Gly. There are no alternative sequences for this arrangement that would satisfy the partial hydrolysis results.

Step by step solution

01

Identify the amino acids in the hydrolysis products

The partial hydrolysis products are Cys-Gly and Glu-Cys. This means that the three amino acids in glutathione are Cysteine (Cys), Glycine (Gly), and Glutamic acid (Glu).
02

Arrange the amino acids based on the partial hydrolysis results

We will use the two partial hydrolysis products to determine the order of the amino acids in the tripeptide glutathione.
03

Use the hydrolysis product Cys-Gly to arrange amino acids

The hydrolysis product Cys-Gly tells us that Cysteine and Glycine are directly connected in the peptide sequence. This gives us the starting point for the first scenario of our peptide sequence: 1. Cys-Gly
04

Use the hydrolysis product Glu-Cys to arrange amino acids

The hydrolysis product Glu-Cys indicates that Glutamic acid and Cysteine are directly connected in the peptide sequence. Considering this, we can now include Glutamic acid in our peptide sequence based on the result from step 3: 1. Glu-Cys-Gly
05

Confirm the arrangement and alternative sequences

Based on the information from the partial hydrolysis products, the only possible arrangement for the amino acids in the tripeptide glutathione is Glu-Cys-Gly. There are no alternative sequences for this arrangement that would satisfy the partial hydrolysis results. Therefore, the glutathione structure is: Glu-Cys-Gly

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

What are the approximate bond angles (a) about carbon in an alkane, (b) about a doubly bonded carbon atom in an alkene, (c) about a triply bonded carbon atom in an alkyne?

What are the characteristic hybrid orbitals employed by (a) carbon in an alkane, (b) carbon in a double bond in an alkene, (c) carbon in the benzene ring, (d) carbon in a triple bond in an alkyne?

Write the condensed structural formulas for as many alkenes and alkynes as you can think of that have the molecular formula \(\mathrm{C}_{6} \mathrm{H}_{10}\)

(a) When cyclopropane is treated with HI, 1-iodopropane is formed. A similar type of reaction does not occur with cyclopentane or cyclohexane. How do you account for the reactivity of cyclopropane? (b) Suggest a method of preparing ethylbenzene, starting with benzene and ethylene as the only organic reagents.

Which of the following peptides have a net positive charge at pH 7? (a) Gly- Ser-Lys, (b) Pro-Leu-Ile, (c) Phe-Tyr-Asp.
See all solutions

Recommended explanations on Chemistry Textbooks

Inorganic Chemistry

Read Explanation

Kinetics

Read Explanation

Ionic and Molecular Compounds

Read Explanation

Nuclear Chemistry

Read Explanation

Chemistry Branches

Read Explanation

The Earths Atmosphere

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free