You are asked to prepare a \(\mathrm{KH}_{2} \mathrm{PO}_{4}-\mathrm{Na}_{2}
\mathrm{HPO}_{4}\) solu-
tion that has the same \(\mathrm{pH}\) as human blood, 7.40
(a) What should be the ratio of concentrations
\(\left[\mathrm{HPO}_{4}^{2-}\right] /\left[\mathrm{H}_{2}
\mathrm{PO}_{4}^{-}\right]\) in this solution?
(b) Suppose you have to prepare \(1.00 \mathrm{L}\) of the solution described in
part (a) and that this solution must be isotonic with blood (have the same
osmotic pressure as blood). What masses of \(\mathrm{KH}_{2} \mathrm{PO}_{4}\)
and of \(\mathrm{Na}_{2} \mathrm{HPO}_{4} \cdot 12 \mathrm{H}_{2} \mathrm{O}\)
would you use? [Hint: Refer to the
definition of isotonic on page \(580 .\) Recall that a solution of
\(\mathrm{NaCl}\) with \(9.2 \mathrm{g} \mathrm{NaCl} / \mathrm{L}\) solution is
isotonic with blood, and assume that \(\mathrm{NaCl}\) is completely ionized in
aqueous solution.]