Chapter 22: Problem 19
Draw the structures of the dipeptides that can be formed from the reaction between the amino acids glycine and alanine.
Chapter 22: Problem 19
Draw the structures of the dipeptides that can be formed from the reaction between the amino acids glycine and alanine.
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Get started for freeConsider the formation of a dimeric protein $$ 2 \mathrm{P} \longrightarrow \mathrm{P}_{2} $$ At \(25^{\circ} \mathrm{C},\) we have \(\Delta H^{\circ}=17 \mathrm{~kJ} / \mathrm{mol}\) and \(\Delta S^{\circ}=\) \(65 \mathrm{~J} / \mathrm{K} \cdot \mathrm{mol}\). Is the dimerization favored at this temperature? Comment on the effect of lowering the temperature. Does your result explain why some enzymes lose their activities under cold conditions?
In Lewis Carroll's tale "Through the Looking Glass," Alice wonders whether "looking-glass milk" on the other side of the mirror would be fit to drink. Based on your knowledge of chirality and enzyme action, comment on the validity of Alice's concern.
Discuss the importance of hydrogen bonding in biological systems. Use proteins and nucleic acids as examples.
Nylon was designed to be a synthetic silk. (a) The average molar mass of a batch of nylon 66 is \(12,000 \mathrm{~g} / \mathrm{mol}\). How many monomer units are there in this sample? (b) Which part of nylon's structure is similar to a polypeptide's structure? (c) How many different tripeptides (made up of three amino acids) can be formed from the amino acids alanine (Ala), glycine (Gly), and serine (Ser), which account for most of the amino acids in silk?
Discuss the characteristics of an amide group and its importance in protein structure.
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