Chapter 20: Problem 477
Describe and give examples of base-catalyzed nucleophilic addition reactions occurring at the carboxy1 carbon.
Chapter 20: Problem 477
Describe and give examples of base-catalyzed nucleophilic addition reactions occurring at the carboxy1 carbon.
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Get started for freeAt \(110^{\circ}\) and \(454 \mathrm{~mm}\) pressure, \(0.11 \mathrm{~g}\) acetic acid vapor occupies \(63.7 \mathrm{cc}\); at \(156^{\circ}\) and \(458 \mathrm{~mm}, 0.081\) g occupies \(66.4 \mathrm{cc}\). Calculate the molecular weight of acetic acid in the vapor phase at each temperature. How do you interpret these results?
Explain the mechanism involved in the nucleophilic substitution reaction on carboxylic acids in esterification.
Outline the synthesis from lauric acid \(\left(\mathrm{n}-\mathrm{C}_{11} \mathrm{H}_{23} \mathrm{COOH}\right.\), dodec- anoic acid) of the following compounds: (a) 1-bromododecane; (b) tridecanoic acid (C \(_{13}\) acid); (c) 1 -tetradecanol; (d) 1 -dodecene; (e) dodecane; (f) 1-dodecyne; (g) methyl n-decy1 ketone; (h) 2-dodecanol; (i) undecanoic acid; (j) 2 -tetra- decanol; (k) 2 -methy \(1-2\) -tetradecanol.
Draw structures for the following: (a) Propionic acid; (b) 2-Chlorobutanoic acid; (c) \(\mathrm{m}\) -Nitrobenzoic acid; (d) Trifluoroacetic acid; (e) 4-Methoxypentanoic acid; (f) a-Bromopropionic acid (g) Isobutyric acid; (h) 2,2-Dibromoheptanoic acid; (i) Formic acid; (i) 3-Benzyl-7-cyclopropyl-heptanoic acid.
What are carboxylic acids? Briefly discuss their properties and the system of naming.
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