Chapter 21: 38P (page 817)
Draw the products of each reaction.
a.
b.
Short Answer
a.
b.
Chapter 21: 38P (page 817)
Draw the products of each reaction.
a.
b.
a.
b.
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Get started for freeConsider the para-substituted aromatic ketones, NO2C6H4COCH2 (p-nitroacetophenone) and CH3OC6H4COCH3 (p-methoxyacetophenone).
a. Which carbonyl compound is more stable?
b. Which compound forms the higher percentage of hydrate at equilibrium?
c. Which compound exhibits a carbonyl absorption at a higher wavenumber in its IR spectrum?
Explain your reasoning in each part.
(a) Explain how in can reduce hemiacetal A to butane-1,4-diol (b) What product is formed when A is treated with ? (c) The drug isotretinoin is formed by the reaction of X and Y. What is the structure of isotretinoin? Although isotretinoin (trade name Accutane or Roaccutane) is used for the treatment of severe acne, it is dispensed under strict controls because it also causes birth defects
Explain why benzaldehyde is less reactive than cyclohexanecarbaldehyde towards nucleophilic attack.
Reaction of 5,5-dimethoxypentan-2-one with methylmagnesium iodide followed by treatment with aqueous acid forms cyclic hemiacetal Y. Draw a stepwise mechanism that illustrates how Y is formed
Draw a stepwise mechanism for the following imine hydrolysis
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