Chapter 29: Q53P (page 1194)
Name each peptide using both the three-letter and one-letter abbreviations of the component amino acids.
a.
b.
Short Answer
- Gly-Asp-Glu and G-D-E.
- Ala-Gly-Arg and A-G-R.
Chapter 29: Q53P (page 1194)
Name each peptide using both the three-letter and one-letter abbreviations of the component amino acids.
a.
b.
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Get started for freeUse the given experimental data to deduce the sequence of an octapeptide that contains the following amino acids: Ala, Gly (2 equiv), His (2 equiv), Ile, Leu and Phe. Edman degradation cleaves Gly from the octapeptide, and carboxypeptidase forms Leu and a heptapeptide. Partial hydrolysis forms the following fragments: Ile-His-Leu, Gly, Gly-Ala-Phe-His, and Phe-His-Ile.
Draw the organic products formed in each reaction
The enolate derived from diethyl acetamidomalonate is treated with each of the following alkyl halides. After hydrolysis and decarboxylation, what amino acid is formed?
a. CH3I
b. (CH3)2CHCH2Cl
c. CH3CH2CH(CH3)Br
Consider two molecules of a tetrapeptide composed of only alanine residues. Draw the hydrogen bonding interactions that result when these two peptides adopt a parallel β-pleated sheet arrangement. Answer this same question for the antiparallel β-pleated sheet arrangement.
Tryptophan is not classified as a basic amino acid even though it has a heterocycle containing a nitrogen atom. Why is the N atom in the five-membered ring of tryptophan not readily protonated by acid?
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