Chapter 18: 8P (page 688)
Draw a stepwise mechanism for the following reaction.
Chapter 18: 8P (page 688)
Draw a stepwise mechanism for the following reaction.
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One step in the synthesis of pioglitazone (trade name Actos), a drug used to treat type 2 diabetes, involves the reaction of A with B in the presence of NaH to afford C. What is the structure of C?
You have learned two ways to make an alkyl benzene: Friedel–Crafts alkylation, and Friedel–Crafts acylation followed by reduction. Although some alkyl benzenes can be prepared by both methods, it is often true that only one method can be used to prepare a given alkyl benzene. Which method(s) can be used to prepare each of the following compounds from benzene? Show the steps that would be used.
Question: Compound X (molecular formula ) was treated with, , to yield compound Y (molecular formula ). Based on theNMR spectra of X and Y were given below, what are the structures of X and Y?
Draw the products formed when A and B are treated with each of the following reagents:
(a),; (b)l3; (c)
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