Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 7: PROBLEM 7.36 (page 286)

Question: Nicotine, a toxic and addictive component of tobacco, is synthesized from A using SAM. Write out the reaction that converts A into nicotine.

Short Answer

Expert verified

ANSWER

Step by step solution

01

Substitution Reactions

The reactions in which a group/atom is substituted/replaced by another are referred to as substitution reactions.

02

SN2 (substitution nucleophilic bimolecular) Reactions

The substitution reactions in which the addition of a nucleophile and the elimination of the leaving group occur simultaneously are referred to as the substitution nucleophilic bimolecular (SN2) reaction.

03

Synthesis of nicotine

The reaction that converts A to nicotine is provided below.

Conversion of A to nicotine

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Question: Rank the following carbocations in order of increasing stability.

a.

b.

c.

Question: Consider the following SN1 reaction.

  1. Draw a mechanism for this reaction using curved arrows.
  2. Draw an energy diagram. Label the axes, starting material, product Eaand ∆H°. Assume that the starting material and product are equal in energy.
  3. Draw the structure of any transition states.
  4. What is the rate equation for this reaction?
  5. What happens to the reaction rate in each of the following instances? [1] The leaving group is changed from I- to Cl-;[2] The solvent is changed from H2O to DMF; [3] The alkyl halide is changed from (CH3)2 C(I) CH2CH3 to (CH3) CHCH(I)CH3 ; [4] The concentration of H2O is increased by a factor of five; and [5] The concentrations of both the alkyl halide and H2O are increased by factor of five.

Question: Draw the products formed when each alkyl halide is treated with NaCN.

a.

b.

Question: Quinapril (trade name Accupril) is used to treat high blood pressure and congestive heart failure. One step in the synthesis of quinapril involves the reaction of the racemic alkyl bromide A with a single enantiomer of the amino ester B. (a) What two products are formed in this reaction? (b) Given the structure of quinapril, which one of these two products is needed to synthesize the drug?

quinapril

Question: Why is the amine N atom more nucleophilic than the amide N atom CH3CONHCH2CH2CH2NHCH3?
See all solutions

Recommended explanations on Chemistry Textbooks

Chemistry Branches

Read Explanation

Physical Chemistry

Read Explanation

Kinetics

Read Explanation

Chemical Reactions

Read Explanation

Nuclear Chemistry

Read Explanation

Making Measurements

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free