Log out Go to App
Go to App

Learning Materials

Features

Discover

Chapter 25: PROBLEM 25.15 (page 1015)

Question: What starting materials are needed to prepare each drug using reductive amination? Give all possible pairs of compounds when more than one route is possible.

a.

b.

Short Answer

Expert verified

Answer

Step by step solution

01

Reduction amination

Reductive amination is the procedure to reduce aldehyde and ketone into amine by the use of reducing agents. The amines can be primary, secondary, or tertiary amines.

02

Reducing agents

The reducing agents are lithium aluminum hydride, sodium cyanoborohydride, and sodium borohydride. These reducing agents produce hydride that reduces the carbonyl compounds.

03

Explanation

a. The given amine compound is obtained by the reduction of ketone, as shown below.

Reduction of ketone in a

b. The given amine compound is obtained by the reduction of ketone, as shown below.

Reduction of ketone in b

Unlock Step-by-Step Solutions & Ace Your Exams!

  • Full Textbook Solutions

    Get detailed explanations and key concepts

  • Unlimited Al creation

    Al flashcards, explanations, exams and more...

  • Ads-free access

    To over 500 millions flashcards

  • Money-back guarantee

    We refund you if you fail your exam.

Start your free trial

Over 30 million students worldwide already upgrade their learning with Vaia!

One App. One Place for Learning.

All the tools & learning materials you need for study success - in one app.

Get started for free

Most popular questions from this chapter

Question: What is the structure of an unknown compound with molecular formula C6H15N that gives the following 1H NMR absorptions: 0.9 (singlet, 1 H), 1.10 (triplet, 3 H), 1.15 (singlet, 9 H), and 2.6 (quartet, 2 H) ppm?

Question: Rank the following compounds in order of increasing basicity

Draw the product Y of the following reaction sequence. Y was an intermediate in the remarkable synthesis of cyclooctatetraene by Wilstatter in 1911.

Question: Give a systematic or common name for each compound.

a.

b.

c.

d.

e.

f.

g.

h.

A chiral amine A having the R configuration undergoes Hofmann elimination to form an alkene B as the major product. B is oxidatively cleaved with ozone, followed by CH3SCH3 , to form CH2=O andCH3CH2CH2CHO .What are the structures of A and B?
See all solutions

Recommended explanations on Chemistry Textbooks

Nuclear Chemistry

Read Explanation

Chemistry Branches

Read Explanation

Making Measurements

Read Explanation

Chemical Analysis

Read Explanation

The Earths Atmosphere

Read Explanation

Physical Chemistry

Read Explanation
View all explanations

What do you think about this solution?

We value your feedback to improve our textbook solutions.

Study anywhere. Anytime. Across all devices.

Sign-up for free