Chapter 29: Q19. (page 1170)
Draw the structure of the N-phenylthiohydantoin formed by initial Edman degradation of each peptide: (a) Ala-Gly-Phe-Phe; (b) Val-Ile-Tyr.
Short Answer
a.
b.
Chapter 29: Q19. (page 1170)
Draw the structure of the N-phenylthiohydantoin formed by initial Edman degradation of each peptide: (a) Ala-Gly-Phe-Phe; (b) Val-Ile-Tyr.
a.
b.
All the tools & learning materials you need for study success - in one app.
Get started for freeThe anti-obesity drug orlistat works by irreversibly inhibiting pancreatic lipase, an enzyme responsible for the hydrolysis of triacylglycerols in the intestines, so they are excreted without metabolism, inhibition occurs by reaction of orlistat with a serine residue of the enzyme, forming a covalently bound, inactive enzyme product. Draw the structure of the product formed during inhibition.
Question:With reference to the following peptide:
(a) Identify the N-terminal and C-terminal amino acids.
(b) Name the peptide using one-letter abbreviations.
(c) Label all the amide bonds in the peptide backbone.
What alkyl halide is needed to synthesize each amino acid from diethyl acetamidomalonate: (a)Asn; (b)His; (c)Trp?
Draw the structure for each peptide:
(a) Phe–Ala;
(b) Gly–Gln;
(c) Lys–Gly;
(d) R-H
Which of the following amino acids are typically found in the interior of a globular protein, and which are typically found on the surface: (a)phenylalanine; (b)aspartic acid; (c) lysine; (d) isoleucine; (e) arginine; (f) glutamic acid?
What do you think about this solution?
We value your feedback to improve our textbook solutions.