Chapter 29: Q40. (page 1193)
What alkyl halide is needed to synthesize each amino acid from diethyl acetamidomalonate: (a)Asn; (b)His; (c)Trp?
Chapter 29: Q40. (page 1193)
What alkyl halide is needed to synthesize each amino acid from diethyl acetamidomalonate: (a)Asn; (b)His; (c)Trp?
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Get started for freeQuestion:Draw the product formed when the following amino acid is treated with each reagent: (a) (b) , pyridine; (c) HCl (1 equiv); (d) NaOH (1 equiv); (e).
a. Draw the structure of the tripeptide A-A-A, and label the two ionizable functional groups.
b. What is the predominant form of A-A-A at pH=1?
c. The values for the two ionizable functional groups (3.39 and 8.03) differ considerably from the values of alanine (2.35 and 9.87;see table 29.1). Account for the observed differences.
Draw all the steps in the synthesis of each peptide from individual amino acids:
(a)Gly-Ala;
(b) Ile-Ala-Phe
Devise a stepwise synthesis of the tripeptide Val-leu-Val from 3-methylbutanal as the only organic starting material. You may also use any required inorganic or organic reagents.
Devise a synthesis of each peptide from amino acid starting materials: (a) Leu–Val; (b) Ala–Ile–Gly.
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